Pilot study to estimate the association between perivascular dysfunction and beta-amyloid burden in subjects with or at risk for Alzheimer’s disease

PI: Michele Cavallari

A visiting research trainee - Fernanda Troili, MD - is evaluating the association between enlarged perivascular spaces (as visible on magnetic resonance imaging) and beta-amyloid burden (as measured by positron emission tomography) in subjects from families carrying gene mutations known to cause familial Alzheimer’s disease, under the mentorship of Drs. Cavallari and Guttmann.