MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information

Citation:

Julien Milles, Yue Min Zhu, Gérard Gimenez, Charles RG Guttmann, and Isabelle E Magnin. 2007. “MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information.” Comput Med Imaging Graph, 31, 2, Pp. 81-90.

Abstract:

A novel approach for correcting intensity nonuniformity in magnetic resonance imaging (MRI) is presented. This approach is based on the simultaneous use of spatial and gray-level histogram information. Spatial information about intensity nonuniformity is obtained using cubic B-spline smoothing. Gray-level histogram information of the image corrupted by intensity nonuniformity is exploited from a frequential point of view. The proposed correction method is illustrated using both physical phantom and human brain images. The results are consistent with theoretical prediction, and demonstrate a new way of dealing with intensity nonuniformity problems. They are all the more significant as the ground truth on intensity nonuniformity is unknown in clinical images.